A GPEI operational guide providing SBC direction for campaigns co-administering nOPV2 and bOPV to respond simultaneously to all three circulating vaccine-derived poliovirus strains. The guide is framed as a living document, to be updated as field experience accumulates.

It covers the epidemiological rationale (drawing on 2024–2025 cVDPV3 detections across Guinea, Chad, Nigeria, Cameroon, and Algeria); the case for co-administration as a single-visit strategy offering comprehensive protection; and the SBC actions needed to make it work — influencer and community leader engagement, IPC training for frontline workers, culturally sensitive messaging, and rumor tracking from campaign outset.

Key messaging pillars are: purpose (why two vaccines), safety (SAGE-endorsed, no injections), familiarity (both are oral drops), effectiveness (full protection against all strains), urgency, and clarity of action for caregivers. Perception and acceptance assessments via FGDs are recommended to ground messaging in community realities, with ongoing feedback loops to enable adaptive strategy.
An FAQ annexure for field use is included.

Best used for: SBC planning for cVDPV outbreak response, co-administration communication, IPC training for frontline workers, caregiver messaging on vaccine safety and dual-dose rationale.